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Cowboys, Lions highlight our best bets of the week



With Week 6’s kickoff less than 24 hours away, we take a look at the NFL odds and make our picks and predictions against the spread. Are there any best bets formulating or is this another week where we will need to make some tough choices? As the NFL standings begin to take shape, what could Week 6 have in store for us?

NFL picks and predictions Week 6 | NFL lines and odds

As injury situations start to become more clear, lines are beginning to fall into place. Let’s take a look at whether there is anything we can take advantage of with our early Week 6 picks and predictions.

Thursday Night Football picks and predictions | Week 6

Here are the Week 6 picks and predictions and NFL odds for Thursday’s game as of 5:30 PM ET on October 13.

Tampa Bay Buccaneers (-6.5) at Philadelphia Eagles

Time and channel: 8:20 PM ET, FOX, NFL Network, and Amazon Prime

For this week’s Thursday Night Football game, the Buccaneers travel to take on the Eagles in Philadelphia. Tom Brady and his squad are laying nearly a touchdown on the road. This line opened up even higher but has slowly shifted in the Eagles’ favor due to a possible thumb injury for Brady.

Last week, Tampa Bay posted an easy 45-17 home victory over Miami. Philadelphia, meanwhile, rallied to defeat Carolina 21-18 on the road.

While the Eagles were able to get the better of Sam Darnold, I don’t expect them to be able to do the same against Brady. The Bucs’ offense is firing on all cylinders right now, ranking third in the league in scoring with 33.4 points per game.

I am not a fan of laying this many points on the road, but it is hard to go against the defending Super Bowl champs in this one.

Buccaneers vs. Eagles Prediction: Buccaneers 34, Eagles 20

Sunday Week 6 NFL picks, predictions, and odds

Here are the Week 6 picks and predictions and NFL odds for Sunday’s games as of 5:30 PM ET on October 13.

Miami Dolphins (-3.5) at Jacksonville Jaguars

Time and channel: 9:30 AM ET, CBS

The expected return of Tua Tagovailoa could not come soon enough for the Dolphins, who have now lost four straight. London has not been a happy hunting ground for Miami, who are 1-3 on the other side of the Atlantic. However, this is a new regime for the Jaguars that will not be used to managing a traveling team.

Both teams have question marks surrounding the future of their head coach. The Dolphins should be the better team, but this could be another London game in the balance in the fourth quarter.

Dolphins vs. Jaguars Prediction: Dolphins 24, Jaguars 21

Time and channel: 1 PM ET, CBS

Before this season kicked off, most Chiefs fans probably circled this game as a possible defeat due to Washington’s supposed elite defensive line. Unfortunately for Washington, the success they had last year has not translated into 2021. With the defense struggling, I think Kansas City is able to right the ship and get an easy win here. Taylor Heinicke has been impressive, especially against good teams. But Patrick Mahomes is in a tier of his own.

Chiefs vs. Washington Prediction: Chiefs 35, Washington 20

Los Angeles Chargers at Baltimore Ravens (-3)

Time and channel: 1 PM ET, CBS

After an impressive come from behind victory Monday night over the Colts, I think Baltimore is in for a let-down spot in Week 6 against the Chargers. Lamar Jackson’s performance in Week 5 was enough to earn him top honors in PFN’s Team of the Week, but Justin Herbert was close behind him.

The Chargers have been lights out on offense this year while Baltimore’s defense has struggled mightily. The Ravens allowed a beat-up Carson Wentz to put up 25 points this past week. Imagine what Herbert will be able to do.

Chargers vs. Ravens Prediction: Chargers 31, Ravens 22

Minnesota Vikings at Carolina Panthers (-1)

Time and channel: 1 PM ET, FOX

After winning their first three games, the Carolina Panthers are spiraling right now. After two losses against NFC East teams, they now return home to take on a Vikings team that is also struggling. Kirk Cousins and the Vikings’ offense have disappeared these past two weeks, and they might struggle against a very good Panthers defense. If Dalvin Cook is out for this game, I like Carolina even more for these Week 6 picks and predictions.

Vikings vs. Panthers Prediction: Panthers 24, Vikings 23

Green Bay Packers (-4.5) at Chicago Bears

Time and channel: 1 PM ET, FOX

The Green Bay Packers travel to Chicago to take on the Bears in this NFC North matchup. We do not know who will be Chicago’s starting quarterback this week, with Justin Fields still nursing an injury from last Sunday. The NFL odds favor the Packers by more than a field goal in this one, and I can understand why. Even though they are on the road, I trust Aaron Rodgers and Davante Adams more than anyone on the Bears’ roster.

Packers vs. Bears Prediction: Packers 24, Bears 14

Cincinnati Bengals (-3) at Detroit Lions

Time and channel: 1 PM ET, FOX

The Bengals are coming off a heartbreaking overtime loss to the aforementioned Packers. Given a number of chances to win the game, kicking was the team’s biggest issue. The Lions also lost because of kicking, and their head coach made it very clear afterward that he is tired of losing.

Even though they are underdogs at home, I think that Detroit is going to play hard for their coach and get their first win of the season. Keep an eye on Joe Burrow’s injury as well — if he is out, this will be one of my best bets for these Week 6 picks and predictions.

Bengals vs. Lions Prediction: Lions 21, Bengals 17

Houston Texans at Indianapolis Colts (-10)

Time and channel: 1 PM ET, CBS

The Houston Texans are still a bad football team, but they played surprisingly well against a decent New England Patriots roster in Week 5. Davis Mills bounced back from a horrendous performance in Week 4 and looked like a very capable rookie. He even did enough to jump a few other rookies in PFN’s Rookie Rankings.

Do I think Mills will do enough to win this one? No. But I do think the Texans can keep it close enough to cover this incredibly large spread. These NFL odds are giving Carson Wentz way too much credit after the Colts’ near-win against the Ravens.

Texans vs. Colts Prediction: Colts 24, Texans 17

Los Angeles Rams (-10.5) at New York Giants

Time and channel: 1 PM ET, FOX

The Los Angeles Rams are laying DOUBLE DIGITS (!) on the road against the New York Giants. With the Giants’ injury issues, I think this spread might actually not be high enough. This game might be played without Saquon Barkley and Daniel Jones, while Kenny Golladay has already been ruled out.

Don’t be too fancy with this one — take Matthew Stafford and the Rams.

Rams vs. Giants Prediction: Rams 34, Giants 20

Arizona Cardinals at Cleveland Browns (-3)

Time and channel: 4:05 PM ET, FOX

This is a clash of two of the best teams in the NFL as the Cardinals look to stay unbeaten. Cleveland’s defense was exposed by the Chargers, but Arizona’s defense is also vulnerable. This should be a high-scoring NFL game, and those are always tough to make picks and predictions for. The Browns need this one more at home, and that could make all the difference.

Cardinals vs. Browns Prediction: Browns 34, Cardinals 30

Las Vegas Raiders at Denver Broncos (-3)

Time and channel: 4:25 PM ET, CBS

After all of the controversy surrounding the Las Vegas Raiders this week, it’s hard to pick them to win against their AFC West rivals in the Denver Broncos. With Jon Gruden now out as head coach, the Raiders might be searching for a new identity. The Broncos have played well this year and are better than their record indicates. Lay the points with Denver as one of my stronger Week 6 picks and predictions.

Raiders vs. Broncos Prediction: Broncos 24, Raiders 14

Dallas Cowboys (-4) at New England Patriots

Time and channel: 4:25 PM ET, CBS

The Patriots were lucky to get a win over the Texans and will now be facing a potential Super Bowl-caliber team in the Dallas Cowboys. My best bet of these Week 6 picks and predictions is on the Cowboys. Their offense is clicking on all levels and their one-two punch with Ezekiel Elliott and Tony Pollard is almost unstoppable. The Cowboys can put up 40 points on anyone in the NFL right now, and I expect them to do so against the Patriots.

Cowboys vs. Patriots Prediction: Cowboys 40, Patriots 20

Seattle Seahawks at Pittsburgh Steelers (-5)

Time and channel: 8:20 PM ET, NBC

This game suddenly looks a lot less star-studded than it did at the start of the season. Geno Smith will go on the road looking to salvage Seattle’s season, which sits precariously at 2-3. The Steelers’ situation is no better, but if they cannot overcome the wounded Seahawks at home, questions will start to mount.

Seahawks vs. Steelers Prediction: Steelers 24, Seahawks 20

Monday Night Football: Week 6 NFL picks and predictions

Here are the Week 6 picks and predictions and NFL odds for Monday’s game as of 5:30 PM ET on October 13.

Buffalo Bills (-4.5) at Tennessee Titans

Time and channel: 8:15 PM ET, ESPN

The Buffalo Bills are arguably the best team in the NFL right now. They just dominated the Kansas City Chiefs and Patrick Mahomes in prime time. Even on the road, the Bills deserve to lay more than a field goal against the Titans. The NFL odds for this one are a little off — continue to bet on Josh Allen to rack up wins.

Bills vs. Titans Prediction: Bills 31, Titans 24

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Would the Dolphins really trade him?




Following internet reports that the Miami Dolphins may be set to trade for Deshaun Watson, additional internet reports — or more specifically, rumors — have emerged. The second set of trade rumors revolves around current Dolphins quarterback Tua Tagovailoa and his future in Miami.

Would the Dolphins really trade him, even if they made a deal for Watson? Back in September, PFN Analyst and Insider Adam Beasley reported that the Dolphins could keep both Tua and Watson on the roster. But have things changed? We’re not sure. If they have, where could Tua land if a trade was completed between the Dolphins and another team?

Tua Tagovailoa Trade Rumors: Potential landing spots

Which teams might be interested in acquiring Tua during just his second year in the league if the Dolphins do, in fact, trade him? There has been lots of speculation around several teams, including the Washington Football Team, Denver Broncos, and the Houston Texans. But are any of them even interested in the second-year quarterback?

Denver Broncos

The Broncos certainly do not have a stable situation at QB. Between Drew Lock’s inconsistent play and Teddy Bridgewater’s one-year prove-it contract, Tua would provide the Broncos another shot at finding their franchise QB. Given the precarious 2022 NFL Draft QB class, the Broncos may feel that the relatively known quantity of Tua is worth the risk.

While the rumors have swirled, there have also been reports that the Broncos are not interested. Given that there is currently uncertainty surrounding the future of the coaching staff in Denver, it would seem odd to throw another QB into an already confusing mix.

Another team with uncertainty at the QB position is Washington. After they lost Ryan Fitzpatrick to a hip injury, Washington has been starting Taylor Heinicke. Heinicke has provided a spark for Washington. However, he’s produced mixed results on the field with 9 touchdowns and 6 interceptions in 2021.

If Washington were to make the move for Tua, he would almost certainly replace Heinicke as the starter when up to speed with the offense. The problem for Washington is that a trade for Tua might signal to the fanbase the team is giving up on the 2021 season at 2-4. Sitting just a game out of a Wild Card spot in the NFC, it’s too early for Washington to throw in the towel.

However, much like with Denver, sources close to the situation are saying that Washington has not been in discussions with Miami or Houston regarding a trade.

Interestingly, the Dolphins and Washington made a similar trade nearly 50 years ago. In 1974, Washington traded a first-round pick in the 1976 NFL Draft to obtain the rights to Joe Theismann from Miami. Theismann would not start at QB for Washington until 1978 but would go on to win a Super Bowl and be named NFL MVP in 1983.

Houston Texans

Naturally, the Houston Texans have to be listed as a potential landing spot. Davis Mills and Tyrod Taylor are unlikely to be the long-term futures of the franchise. And if Watson is leaving, taking a flyer on Tua would make sense. The problem is that acquiring Tua would reduce the draft pick package the Texans would receive for Watson.

If Tua then turns out not to be the answer, the Texans would likely have cost themselves a reasonably high-value draft pick by acquiring Tua. If they were to make the move, Houston would need to feel confident that they could maximize Tua’s value on his rookie contract. Looking at their roster, the Texans do not appear to be in the situation to do that right now.

Pittsburgh Steelers

The end of Ben Roethlisberger’s time in Pittsburgh is not far away. The veteran QB is in clear decline, and the Steelers need a plan for the future. That plan does not appear to be on their roster at the moment, and Pittsburgh will likely have to use significant draft capital to acquire its QB of the future. A trade for Tua could be the quickest answer to preventing an entire rebuild.

New Orleans Saints

The Saints are still looking for a replacement for Drew Brees. They have a QB-friendly offense that has been built on a short, sharp passing game. That is exactly what Tua has been running in Miami. Sean Payton and the Saints simply do it better. Imagine the parallel if the Dolphins trade Tua to be Brees’ replacement, only for Tua to be the long-term answer for that franchise?

What would a trade package look like for Tua?

We rarely witness a situation quite like this one. A top college player who was selected as a top-five pick in his draft is seemingly available within two years of being selected — and during the season, to boot. We rarely see top-tier quarterbacks traded, and when we do, it’s usually later in their careers.

This past offseason, Matthew Stafford was traded for two first-round picks, a third-round pick, and Jared Goff. Some of that cost seemed to account for Detroit taking on Goff’s huge contract, but a fair chunk was just the price of acquiring Stafford.

Now, by no means is Tua as good as Stafford. However, the potential that Tua carries is the key to any valuation. If a team believes Tua still has the potential to be a top-10 quarterback, they might be willing to pay a little more than many expect.

Valuing Tua right now is almost impossible. He has started just 12 games in his career and spent his first season recovering from an extremely serious hip injury that he suffered in his final year at college. Through those 12 games, Tua has 14 touchdowns, 7 interceptions, a 64.1% completion rate while averaging 181.4 yards per game and 6.4 yards per attempt. Not exactly world-beating numbers, but not horrific either.

The Josh Rosen trade could give us a blueprint for Tua’s asking price

The trade for Josh Rosen is a pretty close example. The biggest difference is that Rosen was traded in the offseason, during the 2019 NFL Draft. Interestingly, it was the Dolphins that acquired Rosen in that deal.

When that trade was made in April 2019, Rosen had started 13 games. He’d thrown 11 touchdowns, 14 interceptions, had a completion rate of 55.2%, and was averaging 162.7 yards per game and 5.8 yards per attempt. The Cardinals dealt Rosen for a 2019 second-round pick and 2020 fifth-round choice after selecting Kyler Murray first overall in the 2019 NFL Draft.

Tua’s numbers are clearly better than Rosen’s. However, the situation is similar in that Miami might trade Tua because they are acquiring another QB. Therefore, while Miami might not have the leverage to command a significantly higher price, it should be at least somewhat more favorable.

Based on the Rosen and Stafford trades, a reasonable package for Tua would be along the lines of a first- and third/fourth-round selection. The intriguing element will be whether the Dolphins trade first Tua away to gain capital to acquire Watson, or if we see him dealt as part of a three-team deal that nets Watson.

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Saints vs. Seahawks prediction, pick, odds, and how to watch the Week 7 game




This New Orleans Saints vs. Seattle Seahawks matchup is a little bit less intriguing than the NFL had originally planned, with Seattle rolling with Geno Smith under center while Russell Wilson is injured. With Seattle hanging onto a thread in the NFC West, will a home game against Jameis Winston be enough to save their season? Here are the TV channels and ways to listen, the current NFL odds, and our pick and prediction for the Saints vs. Seahawks game.

New Orleans Saints vs. Seattle Seahawks prediction and odds | Week 7

  • Spread: Saints -5
  • Moneyline: Saints -226, Seahawks +188
  • Over/Under: 43.5 (Over -110, Under -110)

Odds from DraftKings sportsbook

Saints vs. Seahawks prediction

For the past several years, a Saints vs. Seahawks game would have been a marquee matchup of future Hall of Fame quarterbacks Drew Brees and Russell Wilson. That is far from what we are going to get in this one. Brees retired this offseason, and Wilson is out until at least Week 10 with a finger injury. So instead, we will be getting Geno Smith and Jameis Winston.

After stepping in for Wilson after the injury, Smith looked good and almost led the team to a comeback victory against the Rams. Unfortunately, the next week they lost to the Steelers in overtime. It was a good effort, but the Seahawks are now below .500.

The Saints, meanwhile, have been up and down all year. During their tour of the NFC East, they lost to the lowly New York Giants but then followed that up with a win against the Washington Football Team. You just never know which version of Winston you are going to get.

Injuries clouding the picture for both Seattle and New Orleans

It’s not only Wilson out for Seattle — there are also question marks surrounding their running back corps. Chris Carson is on IR with a neck injury, and his replacement Alex Collins, who played well last week, will also miss this matchup. That means Rashaad Penny will likely get the bulk of the carries for the Seahawks.

Things are not much better for New Orleans. Their injury report includes offensive linemen Erik McCoy and Terron Armstead, defensive end Marcus Davenport, linebacker Kwon Alexander, and others.

With both teams beat up, I think the play is to the under 43.5. Both offenses will struggle, and I have little faith that Smith will be able to accomplish much this time around.

Saints vs. Seahawks Prediction: Saints 17, Seattle 10

How to watch and listen to Saints vs. Seahawks this week

  • Start time: 8:15 PM ET
  • Channel: ESPN
  • Live stream:
    • Hulu + Live TV
    • fuboTV
    • YouTube TV
    • DirecTV NFL Sunday Ticket
    • NFL Mobile App
    • NFL GamePass
  • Listen:
    • Local Seattle: 710 ESPN Seattle, KIRO Radio 97.3, & Westwood One
    • Local New Orleans: WWL 870 AM/105.3 FM
    • TuneIn Radio
    • Sirius XM Radio

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Colts vs. 49ers prediction, pick, odds, and how to watch the Week 7 game




The Colts vs. 49ers is a battle between two very different teams. On one side, you have the Colts, who are coming off a dominant performance against the Texans. On the other, you have the 49ers, who still have questions at the QB position and are now coming off a bye. Here’s the channel for the Week 7 contest, the current NFL odds, and a pick and prediction.

Indianapolis Colts vs. San Francisco 49ers prediction and odds | Week 7

  • Spread: San Francisco 49ers -3.5
  • Moneyline: 49ers -210, Colts +175
  • Over/Under: 45 (Over -110, Under -110)
  • Odds from DraftKings sportsbook.

The Indianapolis Colts come into this game looking to build off their 31-3 win over the Houston Texans last week. They are still a long way from the top of the AFC South at 2-4, but a somewhat easy schedule in the coming weeks could put them back in contention.

Carson Wentz has thrown for 1,545 yards, 9 touchdowns, and an interception on 64.2% passing so far this year, and he looks more and more comfortable in the Indianapolis’ offense as the season progresses. Meanwhile, Jonathan Taylor has rushed for a team-high 472 yards and 4 touchdowns. His game against Houston was his best of the year, and he is finally falling into the RB1 role that everyone imagined for him.

The 49ers are coming off a bye but suffered a tough 17-10 loss to the Cardinals the week before. They played Arizona well, and in hindsight, a one-TD loss to the only undefeated team in the NFL is not a bad thing. The bigger problem is that they’re dealing with two banged-up QBs in Jimmy Garoppolo and Trey Lance and a mess at the RB position. It still isn’t clear who their lead back will be in this contest.

Colts vs. 49ers prediction

If you had asked me this question at the beginning of the season, I never would have thought of predicting a possible upset for the Colts on the road against San Francisco. However, here we are. Indianapolis is 7-2 ATS in their last nine road games and 4-1 ATS in their last five contests overall. Wentz is playing like the best QB in this matchup, and as great as the 49ers’ coaching staff is, they have their hands tied behind their backs due to injuries.

Colts vs. 49ers prediction: Colts 24, 49ers 21

How to watch and listen to Colts vs. 49ers this week

  • Start time: 8:20 PM ET
  • Channel: NBC
  • Live stream: 
    • Sling
    • NBC App
    • Hulu + Live TV
    • fuboTV
    • YouTube TV
    • DirecTV NFL Sunday Ticket
  • Listen:
    • Local Indianapolis: Indianapolis on 93.5 & 107.5 The Fan and 97.1 HANK FM.
    • Local San Francisco: KGO 810 AM and KSAN 107.7 FM The Bone
    • TuneIn Radio
    • Sirius XM Radio

Ryan Gosling is the Chief Written Content Officer for Pro Football Network. Follow him on Twitter @ryangoslingPFN.

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